Featured publications

PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

Niemi, N.M.*, Serrano L.R., Muehlbauer L. K., Balnis C. E., Wei, L., Smith A.J., Kozul, K., Forny, M., Connor O.M., Rashan E.H., Shishkova E., Schueler K.L., Keller M.P., Attie A.D., Friedman, J.R., Pagan J., Coon J.J., and D.J. Pagliarini. 2023. Nat Commun. 14(1):6431.

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The extensive and functionally uncharacterized mitochondrial phosphoproteome

Niemi, N.M., and D.J. Pagliarini. 2021. J. Biol. Chem. https://doi.org/10.1016/j.jbc.2021.100880

Pptc7 is an essential phosphatase for promoting mitochondrial metabolism and biogenesis

Niemi, N.M., Wilson, G.M., Overmyer, K.A., Vogtle, F.N., Lohman D.C., Schueler, K.L., Attie, A.D., Meisinger C., Coon, J.J., and D.J. Pagliarini. 2019. Nat Commun. 10(1):3197. PMID: 31324765

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Integrative Proteomics and Biochemical Analyses Define Ptc6p as the Saccharomyces cerevisiae Pyruvate Dehydrogenase Phosphatase

Guo X., Niemi N.M., Coon J.J., and D.J. Pagliarini. 2017. J. Biol. Chem. 292(28):11751-11759. PMID: 28539364

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Ptc7p dephosphorylates select mitochondrial proteins to enhance metabolic function

Guo X.*, Niemi N.M.*, Hutchins, P.D., Condon, S.G.F., Jochem, A., Ulbrich, A., Higbee, A.J., Russell, J.D., Senes, A., Coon, J.J., and D.J. Pagliarini. 2017. Cell Rep. 18(2):307-13. *Co-first author. PMID: 28076776

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A quantitative map of the liver mitochondrial phosphoproteome reveals post-translational control of ketogenesis

Grimsrud, P.A.*, Carson, J.J.*, Hebert, A.S., Hubler, S.L., Niemi, N.M., Bailey, D.J., Jochem, A., Stapleton, D.S., Keller, M.P., Westphall, M.S., Yandell, B.S., Attie, A.D., Coon, J.J., and D.J. Pagliarini. 2012. Cell Metab. 16(5): 672-83. *Co-first author

 

The faculty-to-faculty mentorship experience: a survey on challenges and recommendations for improvements

Sarabipour S.*, Niemi, N.M.*, Burgess S.J.*, Smith C.T., Bisson Filho A.W., Ibrahim A., and K. Clark 2023. Proc Biol Sci. 290(2013):20230983. *Co-first author

Our latest work

 

The pyruvate dehydrogenase complex regulates mitophagic selectivity independently of its catalytic activity

Kolitsida P., Nolic V., Zhou J., Niemi N.M., Dengjel J., and H. Abeliovich. 2023. Life Sci Alliance. 6(9):e202302149.

Enhanced immunoprecipitation techniques for the identification of RNA-binding protein partners: IGF2BP1 interactions in mammary epithelial cells

Fakhraldeen S.A., Berry S.M., Beebe D.J., Roopra A., Bisbach C.M., Spiegelman V.S., Niemi N.M. and C.M. Alexander. 2022. J. Biol. Chem. volume 298, issue 3, 101649.

Quantitative shotgun proteome analysis by direct infusion

Meyer J.G., Niemi N.M., Pagliarini D.J., and J.J.Coon. 2020. Nature Methods volume 17, pages1222–1228.

A survey-based analysis of the academic job market

Fernandes J.D., Sarabipour S., Smith C.T., Niemi N.M., Jadavji N.M., Kozik A.J., Holehouse A.S., Pejaver V., Symmons O., Bisson Filho A.W., and A. Haage. eLife 2020;9:e54097

DOI: 10.7554/eLife.54097.

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